Tetrahedron Letters

Synthesis of potential chemotherapic quinoxalinone derivatives by biocatalysis or microwave-assisted Hinsberg reaction

J Gris, R Glisoni, L Fabian, B Fernández, AG Moglioni

文献索引：Gris, Javier; Glisoni, Romina; Fabian, Lucas; Fernandez, Beatriz; Moglioni, Albertina G. Tetrahedron Letters, 2008 , vol. 49, # 6 p. 1053 - 1056

全文：HTML全文

被引用次数: 56

摘要

In recent years, great efforts have been dedicated to the design of compounds acting as selective inhibitors of the HIV-1 reverse transcriptase (RT). Due to the promissory results previously attained with some quinoxaline derivatives, we aimed to improve the specific standard Hinsberg synthetic pathway by means of biocatalysis or microwave (MW) irradiation. Both techniques rendered the products in very good yields. However, ...