Recent developments in the palladium-catalyzed amination of aryl halides1-7 offer considerable advantages over the classical methods, which require either activated substrates or severe reaction conditions. 8 While these new methods, based on the use of the monophosphine ligand P (o-tolyl) 3 or bis-phosphine ligands BINAP and DPPF, lead to efficient coupling of primary amines and secondary cyclic amines, the arylation of ...
