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Preparative methods for ergoline synthons: Uhle's ketone and the C-homo analog

GS Ponticello, JJ Baldwin, PK Lumma…

文献索引:Ponticello, G.S.; Baldwin, J.J.; Lumma, P.K.; McClure, D.E. Journal of Organic Chemistry, 1980 , vol. 45, # 21 p. 4236 - 4238

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被引用次数: 16

摘要

11n= j L analogous sequence. In this case, the overall yield for the cyclization- decarboxylation conversion of 13 to 15 was in the range of 50-8070. Under these basic nucleophilic conditions, the side reactions available to the reactant under the Bowman process were apparently eliminated, thereby producing satisfactory yields of 15. The possibility of conducting this Dieckmann cyclization-decarboxylation in a combined two- ...