Activation of the phase II enzymes for neuroprotection by ginger active constituent 6-dehydrogingerdione in PC12 cells

J Yao, C Ge, D Duan, B Zhang, X Cui…

文献索引：Zhang, Liangwei; Duan, Dongzhu; Liu, Yaping; Ge, Chunpo; Cui, Xuemei; Sun, Jinyu; Fang, Jianguo Journal of the American Chemical Society, 2014 , vol. 136, # 1 p. 226 - 233

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被引用次数: 13

摘要

The cellular endogenous antioxidant system plays pivotal roles in counteracting or retarding the pathogenesis of many neurodegenerative diseases. Molecules with the ability to enhance the antioxidant defense thus are promising candidates for neuroprotective drugs. 6- Dehydrogingerdione (6-DG), one of the major components of dietary ginger, has received increasing attention due to its multiple pharmacological activities. However, how this ...