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Synthesis and Biological Activity of 3-[2-(Dimethylamino) ethyl]-5-[(1, 1-dioxo-5-methyl-1, 2, 5-thiadiazolidin-2-yl) methyl]-1H-indole and Analogs: Agonists for the 5- …

…, MS Beer, JA Stanton, K Scholey

文献索引:Arya, V. P.; Nagarajan, K.; Shenoy, S. J. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1982 , vol. 21, # 10 p. 941 - 944

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被引用次数: 58

摘要

... MeHN;7\\e 0 0 "'")JT-J$ H H 4: Sumatriptan 3: AH 250866 ... Alcohols 23 and 25 were found to couple with 10b under the normal Mitsunobu conditions (Ph3P, DEAD, THF, 25 "C) to give 26d,k in 534 and 80% yields, respectively. ... Journal of Medicinal Chemistry, 1994, Vol. 37, No. ...