Tetrahedron: Asymmetry

An efficient route for the allylation of arylaldehydes to give enantiopure homoallylic alcohols

PB Thorat, SV Goswami, SR Bhusare

文献索引：Thorat, Prashant B.; Goswami, Santosh V.; Bhusare, Sudhakar R. Tetrahedron Asymmetry, 2013 , vol. 24, # 20 p. 1324 - 1330

全文：HTML全文

被引用次数: 3

摘要

Abstract An efficient asymmetric synthesis of homoallylic alcohols is described by the allylation of carbonyl compounds using organocatalysts as chiral directors in the presence of tin metal. The effect of chiral environment is also studied on the allylation reactions. This method allows us to obtain two different enantiomers of homoallylic alcohol in the presence of the corresponding chiral compound. The protocol is applied to various aldehydes to ...