Chemistry Letters

Chemoenzymatic Synthesis of Both Enantiomers of Fluoxetine.

R Chenevert, G Fortier

文献索引：Chenevert, Robert; Fortier, Genevieve Chemistry Letters, 1991 , p. 1603 - 1606

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被引用次数: 18

摘要

CHEMISTRY LETTERS, pp. 1603 —1606, 11991. © 1991 The Chemical Society of Japan Chemoenzymatic Synthesis of Both Enantiomers of Fluoxetine Robert CHENEVERT* and Genevieve FORTlER Département de chimie, Faculté des sciences at de génie, Université Laval, Quebec, (Quebec) Canada G1 K 7P4 Both enantiomers of fluoxetine have been synthesized from ethyl benzoylacetate. The key step is the enantioselective reduc tion of the starting material by ...