Synthesis and antibacterial activities of novel C (3)-aminopyrimidinyl substituted cephalosporins including against respiratory tract pathogens

…, EJ Ryu, SH Oh, KS Paek, MY Kim, H Youn

文献索引：Lee, Chang-Seok; Ryu, Eun-Jung; Ho Oh, Seong; Paek, Kyoung-Sook; Kim, Mu Yong; Youn, Hasik Bioorganic and Medicinal Chemistry Letters, 2000 , vol. 10, # 18 p. 2123 - 2127

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被引用次数: 8

摘要

The variety of cephalosporins 1 and 2 which possessed C (3)-aminopyrimidinyl substituents were prepared and evaluated for their antibacterial activities. They exhibited excellent in vitro activities especially against respiratory tract pathogens such as penicillin resistant Streptococcus pneumonia, Moraxella catarrhalis and Haemophilus influenza.