3 4 and in efforts to define the relative and complementary scope of the 1, 2, 4-triazine4p5 versus 1, 3-oxazin-6-one6-+ pyridine Diels-Alder reactions applicable to the total synthesis of rubrolone, we have examined the potential for unactivated 1, 3-oxazin-6-one participation in inverse electron demand Diels-Alder reactions. Herein we detail the preparation of 4- methyl-2-propyl-l, 3-oxazin-6-one (3), the scope of its participation in [4+ 21 cycloaddition ...
