An efficient dual synthetic manifold for 2-aminofurans and 2-unsubstituted furans has been developed. The carbenoid-mediated [3+ 2] cycloaddition of copper carbenoids with enamines provides 2-amino-2, 3-dihydrofurans which serve as common intermediates for both 2-aminofurans and 2-unsubstituted furans.
[Staudinger; Gaule Chemische Berichte, 1916 , vol. 49, p. 1915 Full Text Show Details Wolff Justus Liebigs Annalen der Chemie, 1902 , vol. 325, p. 137 Justus Liebigs Annalen der Chemie, 1912 , vol. 394, p. 46 Anm. 2]
