Tetrahedron Letters

Toward waste-free peptide synthesis using ionic reagents and ionic liquids as solvents

N Galy, MR Mazières, JC Plaquevent

文献索引：Galy, Nicolas; Mazieres, Marie-Rose; Plaquevent, Jean-Christophe Tetrahedron Letters, 2013 , vol. 54, # 21 p. 2703 - 2705

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被引用次数: 6

摘要

Some years ago, we disclosed our first approach about peptide synthesis in ionic liquids, in which we described that these unconventional solvents were quite convenient for this process. Indeed, we observed high conversions even for the coupling of hindered amino acids, as well as purification simplified thanks to the rather pure crude material obtained. 7 Most of these results, along with other aspects of ionic liquids related to peptide chemistry, have ...