A facile chemoenzymatic route to enantiomerically pure oxiranes: building blocks for biologically active compounds

U Goergens, MP Schneider

文献索引：Goergens, Ulrich; Schneider, Manfred P. Journal of the Chemical Society, Chemical Communications, 1991 , # 16 p. 1064 - 1066

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被引用次数: 23

摘要

Enantiomerically pure oxiranes are versatile building blocks for the preparation of optically pure natural products, pharmaceuticals and polymers.1 In spite of the availability of numerous methods for the synthesis of these compounds a short and facile route leading with high chemical yield to enantiomerically pure oxiranes would be very useful. In view of our previous work in this area we felt that an ester hydrolase-catalysed resolution of suitable precursors may provide an ...