Journal of Heterocyclic Chemistry

The synthesis of deuterium labeled macrocyclic polyethers (crown ethers)

RR Whitney, DA Jaeger

文献索引：Whitney, Richard R.; Jaeger, David A. Journal of Heterocyclic Chemistry, 1980 , vol. 17, p. 1093 - 1095

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被引用次数: 3

摘要

Abstract Five tetradeuterated analogues (1a, 1b, 1c, 1d, and 1e) of 3, 6, 9, 12, 15-pentaoxa- 21-aza-bicyclo [15.3. 1] heneicosa-1 (21), 17, 19-triene (pyridyl-18-crown-6, 1) have been prepared corresponding to the five unique protonated carbon atoms of the polyether cycle. Deuterium labeling was≥ 99% for four of the compounds and≥ 97% for the other (1a).