Chemistry Letters

Efficient activation of acetals toward nucleophiles with [Rh (COD) Cl] 2 catalyst. New method for the preparation of aldols from acetals and silyl enol ethers by the …

T Mukaiyama, T Soga, H Takenoshita

文献索引：Mukaiyama, Teruaki; Soga, Tsunehiko; Takenoshita, Haruhiro Chemistry Letters, 1989 , p. 1273 - 1276

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被引用次数: 7

摘要

In the presence of a catalytic amount of [Rh (COD) Cl] 2, di-μ-chloro-bis (1, 5- cyclooctadiene) dirhodium, trimethylsilyl cyanide smoothly reacts with acetals derived from aliphatic, unsaturated and aromatic aldehydes to form the corresponding α-cyano derivatives in high yields. In the coexistence of catalytic amounts of [Rh (COD) Cl] 2 and trimethylsilyl cyanide, silyl enol ethers also react with acetals to yield the corresponding ...