N-3-substituted pyrimidinones as potent, orally active, AT1 selective angiotensin II receptor antagonists

A Salimbeni, R Canevotti, F Paleari…

文献索引：Journal of Medicinal Chemistry, , vol. 38, # 24 p. 4806 - 4820

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被引用次数: 53

摘要

... Considerable efforts in the design and synthesis of novel analogues of this lead compound have been performed by several pharmaceutical laboratories. ... f No BSA was included in the assay mixture. Page 5. 4810 Journal of Medicinal Chemistry, 1995, Vol. 38, No. 24 ...