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The Journal of organic chemistry

Synthesis of the Conformationally Constrained Tyrosine Analogues,(R)-and (S)-5-Hydroxy-2-aminoindan-2-carboxylic Acids

FN Murigi, GS Nichol, EA Mash

文献索引:Murigi, Francis N.; Nichol, Gary S.; Mash, Eugene A. Journal of Organic Chemistry, 2010 , vol. 75, # 4 p. 1293 - 1296

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被引用次数: 8

摘要

The conformationally constrained tyrosine analogues,(R)-and (S)-5-hydroxy-2-aminoindan- 2-carboxylic acids, were prepared by chromatographic separation of diastereomeric dipeptide derivatives formed from N-Boc-l-phenylalanine. Absolute configurations were assigned by X-ray crystallographic analysis.