Abstract Aiming at preparation of biologically active compounds a bromination of N, N'- substituted malonodiamides in a glacial acetic acid was carried out. The use of one equiv of bromine provided monobromo derivatives, with two equiv of bromine dibromo-substituted products were obtained. Among the N, N'-dibenzylamides of alkylmalonic acids only the methyl homolog underwent bromination. The structure of compounds was proved by IR ...
