Journal of the American Chemical Society

Torands: Rigid toroidal macrocycles. Calcium sequestration by a member of this new ligand class

TW Bell, A Firestone

文献索引：Bell,T.W.; Firestone,A. Journal of the American Chemical Society, 1986 , vol. 108, p. 8109

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被引用次数: 49

摘要

Figure 1. Synthesis of torand 2 as its calcium triflate complex:(a) MCPBA, CH2C12;(b) Acto, 110 OC;(c) 3 M HCI, 100 OC;(d) Cr03, HOAc, H20, H, S04;(e) Me2NNH2, cyclohexane, EtOH-H20;(f) Me30BF4, CH2C12;(9) 210-230 OC, N, flow;(h) Ac20, AcCI, NaOAc, 100 OC;(i) Ac20, C, H, CHO, reflux; 0') Dess-Martin periodinane, CH3CN (oxidation of H2S04 salts);(k) 35% from 8;(1) 0.5 M H2SO4, distillation of excess C, H, CHO;(m) 46% from 6;(n) 31% ...