Reactions of 1, 2, 4??triazines with nitromethide ion. A convenient method of preparation of 1, 2, 4??triazin??5??ylcarbaldehyde oximes and their synthetic applications
A Rykowski, D Branowska, M Makosza…
文献索引：Rykowski, Andrzej; Branowska, Danuta; Makosza, Mieczyslaw; Van Ly, Phan Journal of Heterocyclic Chemistry, 1996 , vol. 33, # 6 p. 1567 - 1571
Abstract An efficient procedure for the preparation of 1, 2, 4-triazin-5-ylcarbaldehyde oximes 2a-f from 1, 2, 4-triazines 1a-f and nitromethide ion is described. The oximes 2c-d were converted into corresponding 5-cyano-1, 2, 4-triazines 6c-d. The latter compounds react easily with various nucleophiles to afford 5-substituted 1, 2, 4-triazines 7a-i and with 1- pyrrolidino-1-cyclohexene to form cyano derivative of 5, 6, 7, 8-tetrahydroisoquinoline 9.
