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Tetrahedron

Efficient synthesis of 4-phosphinoyl-4, 5, 6, 7-tetrahydro-2H-indazol-3-ylamines

N Jelaiel, C Comoy, B Fernette, ML Efrit, Y Fort

文献索引:Jelaiel, Nourchaine; Comoy, Corinne; Fernette, Brigitte; Efrit, Mohamed Lofti; Fort, Yves Tetrahedron, 2011 , vol. 67, # 48 p. 9440 - 9445

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被引用次数: 26

摘要

Because of their chemical and/or biological significance, nitrogen containing heterocycles represent an important and attractive area of organic chemistry. Among various series of heterocycles, we focused our attention on indazolyl moieties. As mentioned in literature, numerous examples of indazolyl heterocycles exhibit biological properties as well as anticoagulating agent, 1 topoisomerase bacterium II inhibitor, 2 or for treatment of hypercholesterol, 3 tuberculosis, 4 … (Fig. 1).