J. Chem. Soc., Perkin Trans. 1

Application of chemical P-450 model systems to studies on drug metabolism. Part X. Novel hydroxylactonization of γ, δ-and β, γ-unsaturated carboxylic acids with an …

M Komuro, T Higuchi, M Hirobe

文献索引：Komuro, Masakatsu; Higuchi, Tsunehiko; Hirobe, Masaaki Journal of the Chemical Society - Perkin Transactions 1, 1996 , # 18 p. 2309 - 2313

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被引用次数: 17

摘要

The oxidative hydroxylactonization of γ, δ-and β, γ-unsaturated carboxylic acids by a chemical cytochrome P-450 model and rat liver microsomal systems has been investigated. In the chemical system using-tetrakis (2, 6-dichlorphenyl) porphyrin iron chloride [Fe (TDCIPP) Cl] with iodosylbenzene (PhIO), γ, δ-unsaturated car