Novel and efficient synthesis and antifungal evaluation of 2, 3-functionalized cholestane and androstane derivatives

…, SK Upadhyay, CC Creech, DM Neumann

文献索引：Jursic, Branko S.; Upadhyay, Sunil Kumar; Creech, Clinton C.; Neumann, Donna M. Bioorganic and Medicinal Chemistry Letters, 2010 ,  vol. 20,  # 24  p. 7372 - 7375

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被引用次数: 8

摘要

Synthetic modifications of cholesterol and other traditional steroid molecules have become a promising area for the exploration and development of novel antifungal agents, especially with respect to the development of fatty-acid esters of steroids. In addition, 2, 3- functionalized steroids are also compounds with potentially interesting biological properties and proper functionalization of 2, 3-steroids can lead to the development of efficient ...