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1-(4-Cyclopentylphenyl) ethylamine and derivatives: Synthesis and pharmacological screening

…, J Holubek, M Bartošová, M Protiva

文献索引:Vejdelek; Holubek; Bartosova; Protiva Collection of Czechoslovak Chemical Communications, 1981 , vol. 46, # 9 p. 2234 - 2244

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被引用次数: 1

摘要

Abstract Reduction of 4-cyclopentylacetophenone oxime gave the title compound II which was transformed by a combination of acylation, alkylation, reduction and substitution reactions to compounds III-XI. 2-Benzylcyclopentanone oxime was reduced to 2- benzylcyclopentylamine (XVI) and converted by a reaction with methylmagnesium iodide and by the following Ritter reaction to the formamide derivative XVIII which was used as ...