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Copper (II) complexes with norfloxacin and neutral terpyridines: cytotoxic, antibacterial, superoxide dismutase and DNA-interaction approach

MN Patel, HN Joshi, CR Patel

文献索引:Patel, Mohan N.; Joshi, Hardik N.; Patel, Chintan R. Polyhedron, 2012 , vol. 40, # 1 p. 159 - 167

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被引用次数: 20

摘要

Cu (II) complexes of the type [Cu (NFL)(Ln) Cl](Ln= substituted terpyridines, NFL= norfloxacin) were synthesised and characterized. Antibacterial activity was assayed against selective Gram (+ ve) and Gram (− ve) microorganisms using the double dilution technique. The binding behavior of the complexes toward Herring Sperm (HS) DNA was determined using absorption titration and hydrodynamic measurements, whereas the cleavage ...