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Synthesis, surface tension properties and antibacterial activities of amphiphilic D-galactopyranose derivatives

L Chaveriat, I Gosselin, C Machut, P Martin

文献索引:Chaveriat, Ludovic; Gosselin, Isabelle; Machut, Cecile; Martin, Patrick European Journal of Medicinal Chemistry, 2013 , vol. 62, p. 177 - 186

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被引用次数: 9

摘要

Several amphiphilic d-galactopyranose derivatives were synthesized in which the glycosidic moiety was separated from the hydrophobic alkyl chain (along 8 or 12 carbon atoms) by a spacer arm (butyl, butynyl or benzyl) in order to increase their surfactant properties and to obtain new antibacterial compounds. The surface tensions of the products were analyzed by Critical Micelle Concentration (CMC) and γCMC measurements and the antimicrobial ...