New synthesis of 1, 2, 4-triazoles and 1, 2, 4-oxadiazoles

YI Lin, SA Lang Jr, MF Lovell…

文献索引：Lin,Y. et al. Journal of Organic Chemistry, 1979 , vol. 44, # 23 p. 4160 - 4164

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被引用次数: 63

摘要

A new synthesis of 1, 2, 4-triazoles and 1, 2, 4-oxadiazoles has been developed. N'-Acyl-N, N-dimethylamidines, which were prepared in excellent yields by reactions of amides with N, N-dimethylalkanamide dimethyl acetals, reacted with hydrazines or hydroxylamine in acetic acid to give 1, 2, 4-triazoles or 1, 2, 4-oxadiazoles, respectively, in excellent yields.