Thermal isomerization of 2, 2-difluoromethylenecyclopropane

WR Dolbier Jr, TH Fielder Jr

文献索引：Dolbier,W.R.; Fielder,T.H. Journal of the American Chemical Society, 1978 , vol. 100, p. 5577 - 5578

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被引用次数: 35

摘要

The effect of a fluorine substituent on the thermodynamic stability of a cyclopropane ring is not quantitatively well un-derstood at present. Our earlier study of the geometrical isomerization of 1, l-difluoro-2, 3-dimethylcyclopropane indicated that gem-difluoro substituents weaken cyclopropane to cleavage by-9 kcal/mol. l However, the only previous work which shed light on the overall thermodynamic effect of fluorine on a cyclopropane ...