Synthesis

Preparation of pyrrole-2-carboxylates with electron-withdrawing groups at the 4-position

H Uno, M Tanaka, T Inoue, N Ono

文献索引：Uno, Hidemitsu; Tanaka, Masanori; Inoue, Takashi; Ono, Noboru Synthesis, 1999 , # 3 p. 471 - 474

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被引用次数: 29

摘要

Abstract: Reaction of a-trifluoromethyl, a-cyano, and a-ethoxycarbonyl alkenyl sulfones with ethyl isocyanoacetate in the presence of a base gave 4-substituted pyrrole-2-carboxylates in moderate to good yields. Key words: pyrrole-2-carboxylate, trifluoromethyl, BartonœZard reaction, alkenyl sulfones