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Studies directed towards the synthesis of antascomicin A: stereoselective synthesis of the C22–C34 fragment of the molecule

TK Chakraborty, BK Mohan, M Sreekanth

文献索引:Chakraborty, Tushar Kanti; Mohan, Bajjuri Krishna; Sreekanth, Midde Tetrahedron Letters, 2006 , vol. 47, # 29 p. 5003 - 5005

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被引用次数: 6

摘要

A stereoselective synthesis of the C22–C34 fragment of the non-immunosuppressive immunophilin-binding natural product, antascomicin A was achieved using d-quinic acid as the starting material and highly stereoselective aldol reactions were employed, as key steps, to build the remaining stereocentres at C23, C26 and C27.