Preliminary Experiments on the Synthesis of Colchicine. The Synthesis of 4b, 5, 6, 7, 8, 8a, 9, 10-Octahydro-2, 3, 4-trimethoxy-10-ketophenanthrene and its B-Ring …
CD Gutsche, FA Fleming
文献索引：Gutsche; Fleming Journal of the American Chemical Society, 1954 , vol. 76, p. 1771,1774
4b, 5, 6, 7, 8, 8a, 9, 10-0ctahydro-2, 3, 4-trimethoxy-lO-ketophenanthrene and its B-ring and C-ring homologs, compounds of interest in syntheses in the colchicine series, have been prepared as follows: 2, 3, 4-Trimethoxyiodobenzene was converted to the Grignard compound by the entrainment method, and this was allowed to react with cyclohexanone or cycloheptanone to yield the corresponding trimethoxyphenylcycloalkene; treatment of the ...
