Studies on Disease-Modifying Antirheumatic Drugs: Synthesis of Novel Quinoline and Quinazoline Derivatives and Their Anti-inflammatory Effect 1

A Baba, N Kawamura, H Makino, Y Ohta…

文献索引：Baba, Atsuo; Kawamura, Noriaki; Makino, Haruhiko; Ohta, Yoshikazu; Taketomi, Shigehisa; Sohda, Takashi Journal of Medicinal Chemistry, 1996 , vol. 39, # 26 p. 5176 - 5182

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被引用次数: 88

摘要

In the course of our study aimed at developing new types of DMARDs (disease-modifying antirheumatic drugs), we found that quinoline derivative 1a had a potent anti-inflammatory effect in an adjuvant arthritis (AA) rat model, starting from the potent bone resorption ...