Synthesis and activity of fluorescent isoprenoid pyrophosphate analogues
…, TS Kleckley, AJ Wiemer, SA Holstein…
文献索引：Kim, MeeKyoung; Kleckley, Troy S.; Wiemer, Andrew J.; Holstein, Sarah A.; Hohl, Raymond J.; Wiemer, David F. Journal of Organic Chemistry, 2004 , vol. 69, # 24 p. 8186 - 8193
New fluorescent analogues of farnesol and geranylgeraniol have been prepared and then converted to the corresponding pyrophosphates. These analogues incorporate anthranylate or dansyl-like groups anchored to the terpenoid skeleton through amine bonds that would be expected to be relatively stable to metabolism. After addition of the alcohols or the pyrophosphates to the culture medium, their fluorescence is readily observed inside a ...
