Synthesis and biological activities of fatty acid conjugates of a cyclic lactam. alpha.-melanotropin
F Al-Obeidi, VJ Hruby, N Yaghoubi…
文献索引：Al-Obeidi, Fahad; Hruby, Victor J.; Yaghoubi, Nader; Marwan, Mohamed M.; Hadley, Mac E. Journal of Medicinal Chemistry, 1992 , vol. 35, # 1 p. 118 - 123
Introduction a-Melanotropin, a-MSH (Ac-Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro- Val-”,), is a tridecapeptide that is biosynthesized and secreted from the pars intermedia of the pituitary gland. 2 This hormone plays an essential role in the adaptive color changes of many animals through its action on integumental melanocyte^.^ The melanotropic peptide appears to regulate other physiological functions as well. 44 Because of an extensive ...
