Studies related to synthesis of glycophosphatidylinositol membrane-bound protein anchors. 6. Convergent assembly of subunits

…, P Konradsson, B Fraser-Reid

文献索引：Madsen, Robert; Udodong, Uko E.; Roberts, Carmichad; Mootoo, David R.; Konradsson, Peter; Fraser-Reid, Bert Journal of the American Chemical Society, 1995 , vol. 117, # 5 p. 1554 - 1565

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被引用次数: 60

摘要

Abstract: Glycophosphatidylinositol anchors of membrane-bound proteins are thought to comprise a common pentasaccharide core containing mannan, glucosamine, and inositol residues. A synthetic route to this core is described. In addition, the complete heptasaccharide moiety of the rat brain Thy-1 membrane anchor, the first mammalian membrane anchor to be characterized, has been synthesized. In the case of the Thy-1 ...