Antitumor agents. V. Synthesis and antileukemic activity of E-ring-modified (RS)-camptothecin analogues.

江島明男， 寺沢弘文， 杉森正道， 大薄悟…

文献索引：Chemical and Pharmaceutical Bulletin, , vol. 40, # 3 p. 683 - 688

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被引用次数: 37

摘要

... Chemistry The camptothecin analogues were prepared by total synthesis. ... constants (RS)-1"' 63 163 148 128 128 114 >3.7 are reported in hertz and chemical shifts in ... and 25d" 26 >189( ) 17; / 151 135 > 9“ 6 toluene were dried over molecular sieves (4 A) (Wako Chemicals). ...