Abstract An environmentally friendly method for the synthesis of a series of novel, unsymmetrical Michler's ketone analogues,[4-(dialkylamino) phenyl](aryl) methanones, via nucleophilic aromatic substitution of (fluorophenyl)(aryl) methanones with various amines in water is described. The reaction products are formed in high yields and additional purification is not required. The aqueous solvent and unreacted amines can be recycled.
