Biological activity evaluation and structure–activity relationships analysis of ferulic acid and caffeic acid derivatives for anticancer

…, Y Tang, B Li, L Liu, X Zhang, H Fu, J Duan

文献索引：Li, Weixia; Li, Nianguang; Tang, Yuping; Li, Baoquan; Liu, Li; Zhang, Xu; Fu, Haian; Duan, Jin-Ao Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 19 p. 6085 - 6088

全文：HTML全文

被引用次数: 23

摘要

The anticancer activities of alkyl esters and NO-donors of ferulic acid (FA) and caffeic acid (CA) were assessed by a high-throughout screening (HTS) method, and the structure– activity relationships were described. CA alkyl esters had better anticancer activities than FA alkyl esters with the same alkyl substituent. Mono-nitrates and phenylfuroxan nitrates were more potent than the dual nitrates. Phenylsulfonylfuroxan nitrates of FA, especially ...