Journal of the American Chemical Society

Macrocyclic inhibitors of penicillopepsin. 1. Design, synthesis, and evaluation of an inhibitor bridged between P1 and P3

JH Meyer, PA Bartlett

文献索引：Gruber, Rene; Cagniant, Denise; Cagniant, Paul Bulletin de la Societe Chimique de France, 1983 , vol. 2, # 3-4 p. 96 - 104

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被引用次数: 111

摘要

... Volume: Page: ... 3 differ in composition from the cyclic analogue 1 by a carbon atom; that is, a methylene unit is replaced by two hydrogens ... For comparison, the van der Waals surface of ethylbenzene is 183 Å 2 , while benzene + methane have 194 Å 2 of surface ...