Synthesis and antiplatelet activity of thioaryloxyacids analogues of clofibric acid

…, M Baraldi, G Bettoni, D Braghiroli, B De Filippis…

文献索引：Ammazzalorso, Alessandra; Amoroso, Rosa; Baraldi, Mario; Bettoni, Giancarlo; Braghiroli, Daniela; De Filippis, Barbara; Giampietro, Letizia; Tricca, Maria L.; Vezzalini, Francesca European Journal of Medicinal Chemistry, 2005 , vol. 40, # 9 p. 918 - 921

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被引用次数: 12

摘要

The thiophene-, benzothiazole-and pyridine-thioaryloxyacids analogues of clofibric acid were synthesized and their antiplatelet activity was screened. Some compounds exhibited antiaggregating properties. The platelet-related haemostasis was measured on a PFA-100® analyzer using bull blood.