Photoswitched DNA-binding of a photochromic spiropyran

…, S Li, P Lincoln, J Andréasson

文献索引：Andersson, Johanna; Li, Shiming; Lincoln, Per; Andreasson, Joakim Journal of the American Chemical Society, 2008 , vol. 130, # 36 p. 11836 - 11837

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被引用次数: 134

摘要

The dramatically different DNA-binding properties of the two isomeric forms of a photochromic spiropyran have been demonstrated, enabling photoswitched DNA binding. The closed, UV-absorbing form shows no signs of interaction with DNA. Upon UV exposure the spiropyran is isomerized to the open form that binds to DNA by intercalation. The process is fully reversible as the corresponding dissociation process is induced by visible ...