Tetrahedron

Enantioselective total synthesis of eudistomidins G, H, and I

H Ishiyama, K Yoshizawa, J Kobayashi

文献索引：Ishiyama, Haruaki; Yoshizawa, Kazuaki; Kobayashi, Jun'ichi Tetrahedron, 2012 , vol. 68, # 31 p. 6186 - 6192

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被引用次数: 14

摘要

Asymmetric first total synthesis of eudistomidins G, H, and I, tetrahydro-β-carboline alkaloids from the Okinawan marine tunicate Eudistoma glaucus, has been accomplished with the Bischler–Napieralski reaction and the Noyori catalytic asymmetric hydrogen-transfer reaction. The absolute configurations of eudistomidins G, H, and I were confirmed from comparison of the 1H and 13C NMR, and CD spectral data of synthetic and natural ...