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Synthesis of chiral pyrrolo [1, 2-c] thiazoles via intramolecular dipolar cycloaddition of münchnones: An interesting rearrangement to pyrrolo [1, 2-c] thiazines

…, AM Beja, MR Silva, L Alte da Veiga…

文献索引:Gilchrist, Thomas L.; Wasson, Robert C.; King, Frank D.; Wootton, Gordon Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1987 , p. 2517 - 2522

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被引用次数: 32

摘要

... Thiazolidine 12 was converted into the 1H,3H-pyrrolo[1,2-c]thiazole 14 using a synthetic ... The acetylated product 15 ([α] D 25 = + 35) was also isolated in 12% yield (Scheme 4 ... The reaction of phenylglyoxal and L-cysteine methyl ester gives also a thiazolidine as a mixture of the ...