Synthesis and structure-activity studies of novel orally active non-terpenoic 2, 3-oxidosqualene cyclase inhibitors

H Dehmlow, JD Aebi, S Jolidon, YH Ji…

文献索引：Westland; Holmes; Green; Dice Journal of medicinal chemistry, 1968 , vol. 11, # 4 p. 824 - 829

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被引用次数: 56

摘要

... Journal of Medicinal ... Further skeletal rearrangements through 1,2-shifts of hydride and methyl substituents yield lanosterol. The first compounds that represented a starting point for medicinal chemistry were found in the chemical collection of a fungicide project. ... Chemistry. ...