Tetrahedron

The biomimetic synthesis of marine alkaloid related pyrido-and pyrrolo [2, 3, 4-kl] acridines

G Gellerman, A Rudi, Y Kashman

文献索引：Gellerman, Gari; Rudi, Amira; Kashman, Yoel Tetrahedron, 1994 , vol. 50, # 45 p. 12959 - 12972

全文：HTML全文

被引用次数: 52

摘要

A biomimetic reaction between β, β′-diamenoketones (eg kynuramine, kynurenine or o, o′-diaminobenzophenone) and a variety cyclohexanediones and quinones leading to pyrido [2, 3, 4-kl) acridines is described. The synthesis of several di-and tetrahydro-pyrido [2, 3, 4-kl) acridine derivatives (7, 10. 12 and 15) as well as benzoderivatives of the marine alkaloids eilatin (1) and ascididemin (2), compounds 28 and 30, has been accomplished. ...