Fluorine containing bioactive heterocycles. Part II. Synthesis of some new fluorine containing arylglyoxals, their hydrates and 1, 5??disubstituted hydantoins

KC Joshi, VN Pathak, MK Goyal

文献索引：Joshi, Krishna C.; Pathak, Vijai N.; Goyal, Mahendra K. Journal of Heterocyclic Chemistry, 1981 , vol. 18, p. 1651 - 1653

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被引用次数: 18

摘要

Abstract Eight new fluorine containing arylglyoxals have been synthesized by the oxidation of the active methyl group of fluorinated acetophenones by selenium dioxide in dioxan-water medium. The corresponding hydrates were obtained by dissolving arylglyoxals in minimum amounts of benzene and adding hot water. Seventeen new fluorine containing 1, 5- disubstituted hydantoins were subsequently prepared by the condensation of these ...