Tetrahedron letters

Reactions of protected amino acid chlorides mediated by SmI 2.

J Collin, JL Namy, G Jones, HB Kagan

文献索引：Collin, J.; Namy, J. L.; Jones, G.; Kagan, H. B. Tetrahedron Letters, 1992 , vol. 33, # 21 p. 2973 - 2976

全文：HTML全文

被引用次数: 11

摘要

Abstract Reactions of N-protected amino acid chlorides with carbonyl compounds in the presence of SmI 2 were investigated. Decarbonylation followed by a cross coupling between amino moiety and aldehyde or ketone is observed. By the use of FMOC derivatives, N- protected amino alcohols were isolated in moderate yields.