Cyclic peroxides. 60. Prostanoid endoperoxide model compounds: preparation of 1, 2-dioxolanes from cyclopropanes

W Adam, A Birke, C Cadiz, S Diaz…

文献索引：Adam; Birke; Cadiz; et al. Journal of Organic Chemistry, 1978 , vol. 43, # 6 p. 1154 - 1158

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被引用次数: 23

摘要

(500 mg, 1.9 mmol) was dissolved in 8 mL of carbon tetrachlorideacetonitrile (1: lv/v) and triphenylphosphine (655 mg, 2.50 mmol) was added. The solution was stirred for 2 h at room temperature. A preparative scale TLC was run (silica gel-10% tetrahydrofuranhexane) on the product to remove triphenylphosphine oxide. Evaporation of solvent gave 410 mg (82%) of a yellow oil which by'H NMR integration of resonances at 6 4.13 and 6 4.27 contained ...