Ring A conformation in steroids. 2—NMR study of C??2 monomethyl??and dimethyl??substituted 5α??androstan??3??ones

…, JF Templeton, RK Gupta, VP Kumar

文献索引：Marat, Kirk; Templeton, John F.; Gupta, R. K.; Kumar, Sashi V. P. Magnetic Resonance in Chemistry, 1987 , vol. 25, p. 730 - 733

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被引用次数: 7

摘要

Abstract Ring A proton shifts and couplings and 13 C shifts of all carbons are given for 17β- acetoxy-2α-methyl-and 17β-methoxy-2β-methyl-5α-androstan-3-one and 2, 2-dimethyl-17β- methoxy-5α-androstan-3-one. It was concluded that the 2β-methyl derivative exists with ring A in a regular chair conformation while the 2β-methyl derivative exists with ring A in an inverted boat conformation with C-2 and C-5 at the bow/stern positions. The data for 2, 2- ...