Discovery of cyantraniliprole, a potent and selective anthranilic diamide ryanodine receptor activator with cross-spectrum insecticidal activity
TP Selby, GP Lahm, TM Stevenson, KA Hughes…
文献索引：Selby, Thomas P.; Lahm, George P.; Stevenson, Thomas M.; Hughes, Kenneth A.; Cordova, Daniel; Annan, I. Billy; Barry, James D.; Benner, Eric A.; Currie, Martin J.; Pahutski, Thomas F. Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 23 p. 6341 - 6345
Abstract Anthranilic diamides are an exceptionally active class of insect control chemistry that selectively activates insect ryanodine receptors causing mortality from uncontrolled release of calcium ion stores in muscle cells. Work in this area led to the successful commercialization of chlorantraniliprole for control of Lepidoptera and other insect pests at very low application rates. In search of lower log P analogs with improved plant systemic ...
