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Stereospecific synthesis of a carbene-generating angiotensin II analogue for comparative photoaffinity labeling: improved incorporation and absence of methionine …

D Fillion, M Deraët, BJ Holleran…

文献索引:Topin, Andrey N.; Gritsenko, Oxana M.; Brevnov, Maxim G.; Gromova, Elisaveta S.; Korshunova, Galina A. Nucleosides and Nucleotides, 1998 , vol. 17, # 7 p. 1163 - 1175

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被引用次数: 23

摘要

... C/rt, 92%; (f) DCC, t-BuOH, Cu(I)Cl, CH 2 Cl 2 , 74 h, rt, 67%; (g) Me(PhO ... Putative sites of N-glycosylation on Asn4, Asn13, Asn24, Asn29, and Asn34 are also indicated. ... Affinities (K d ) are presented in nM, and maximum binding capacities (B m ax ; established with 125 I-13) are ...